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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCL1
All Species:
22.73
Human Site:
Y431
Identified Species:
38.46
UniProt:
Q15111
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15111
NP_006217.3
1095
122728
Y431
G
P
A
D
I
N
G
Y
I
R
A
L
K
M
G
Chimpanzee
Pan troglodytes
XP_001169560
1095
122728
Y431
G
P
A
D
I
N
G
Y
I
R
A
L
K
M
G
Rhesus Macaque
Macaca mulatta
XP_001089483
1095
122754
Y431
G
P
A
D
I
N
G
Y
V
R
A
L
K
M
G
Dog
Lupus familis
XP_536020
1096
122535
Y432
G
P
A
D
I
N
G
Y
V
R
A
L
K
M
G
Cat
Felis silvestris
Mouse
Mus musculus
Q3USB7
1096
122654
Y432
G
P
A
D
I
N
G
Y
V
R
A
L
K
M
G
Rat
Rattus norvegicus
Q62688
1096
122754
Y432
G
P
A
D
I
N
G
Y
V
R
A
L
K
M
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507313
1051
118878
E395
K
M
G
C
R
S
V
E
L
D
V
W
D
G
P
Chicken
Gallus gallus
Q2VRL0
637
72514
V49
K
H
V
F
K
K
T
V
D
K
R
K
I
H
T
Frog
Xenopus laevis
Q32NH8
758
87399
V168
D
L
L
K
M
M
N
V
D
M
S
E
H
H
A
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
N196
Q
L
I
N
I
D
L
N
E
Q
Y
A
R
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13217
1095
124845
F403
Q
A
I
A
D
C
A
F
V
S
S
E
Y
P
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_741067
1068
120024
R399
S
A
L
K
R
N
C
R
F
L
E
F
D
I
W
Sea Urchin
Strong. purpuratus
XP_001178766
684
77475
F96
T
Q
S
L
S
H
Y
F
I
A
A
S
H
N
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32383
869
100529
A281
L
L
E
F
F
Q
L
A
D
I
N
H
N
G
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
98.7
96.4
N.A.
94.3
94.1
N.A.
62.9
21.7
24.7
27.9
N.A.
20
N.A.
39
35.8
Protein Similarity:
100
100
99.2
98.5
N.A.
96.6
96.6
N.A.
77.1
34.8
40.4
42.3
N.A.
40.2
N.A.
59.4
48.1
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
93.3
N.A.
0
0
0
6.6
N.A.
0
N.A.
6.6
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
6.6
13.3
33.3
N.A.
20
N.A.
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
43
8
0
0
8
8
0
8
50
8
0
0
8
% A
% Cys:
0
0
0
8
0
8
8
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
43
8
8
0
0
22
8
0
0
15
0
0
% D
% Glu:
0
0
8
0
0
0
0
8
8
0
8
15
0
0
0
% E
% Phe:
0
0
0
15
8
0
0
15
8
0
0
8
0
0
0
% F
% Gly:
43
0
8
0
0
0
43
0
0
0
0
0
0
15
43
% G
% His:
0
8
0
0
0
8
0
0
0
0
0
8
15
15
0
% H
% Ile:
0
0
15
0
50
0
0
0
22
8
0
0
8
8
0
% I
% Lys:
15
0
0
15
8
8
0
0
0
8
0
8
43
0
0
% K
% Leu:
8
22
15
8
0
0
15
0
8
8
0
43
0
0
15
% L
% Met:
0
8
0
0
8
8
0
0
0
8
0
0
0
43
0
% M
% Asn:
0
0
0
8
0
50
8
8
0
0
8
0
8
8
0
% N
% Pro:
0
43
0
0
0
0
0
0
0
0
0
0
0
8
8
% P
% Gln:
15
8
0
0
0
8
0
0
0
8
0
0
0
0
0
% Q
% Arg:
0
0
0
0
15
0
0
8
0
43
8
0
8
0
0
% R
% Ser:
8
0
8
0
8
8
0
0
0
8
15
8
0
0
0
% S
% Thr:
8
0
0
0
0
0
8
0
0
0
0
0
0
8
15
% T
% Val:
0
0
8
0
0
0
8
15
36
0
8
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% W
% Tyr:
0
0
0
0
0
0
8
43
0
0
8
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _